Work productivity in rhinitis using cell phones: The MASK pilot study.
Identifieur interne : 000037 ( Main/Exploration ); précédent : 000036; suivant : 000038Work productivity in rhinitis using cell phones: The MASK pilot study.
Auteurs : J. Bousquet [France] ; M. Bewick [Royaume-Uni] ; S. Arnavielhe [France] ; E. Mathieu-Dupas [France] ; R. Murray [Irlande (pays)] ; A. Bedbrook [France] ; D P Caimmi [France] ; O. Vandenplas [Belgique] ; P W Hellings [Belgique] ; C. Bachert [Belgique] ; J M Anto [Espagne] ; K C Bergmann [Allemagne] ; C. Bindslev-Jensen [Danemark] ; S. Bosnic-Anticevich [Australie] ; J. Bouchard [Canada] ; G W Canonica [Italie] ; N H Chavannes [Pays-Bas] ; A A Cruz [Brésil] ; R. Dahl [Brésil] ; P. Demoly [France] ; G. De Vries [Pays-Bas] ; P. Devillier [France] ; A. Fink-Wagner [Autriche] ; W J Fokkens [Pays-Bas] ; J. Fonseca [Portugal] ; N A Guldemond [Pays-Bas] ; T. Haahtela [Finlande] ; B. Hellqvist-Dahl [Danemark] ; J. Just [France] ; T. Keil [Allemagne] ; L. Klimek [Allemagne] ; M L Kowalski [Pologne] ; P. Kuna [Pologne] ; V. Kvedariene [Lituanie] ; D. Laune [France] ; D. Larenas-Linnemann [Mexique] ; J. Mullol [Espagne] ; A M Pereira [Portugal] ; P. Carreiro-Martins [Portugal] ; E. Melén [Suède] ; M. Morais-Almeida [Portugal] ; L. Nogueira-Silva [Portugal] ; R E O'Hehir [Australie] ; N G Papadopoulos [Royaume-Uni] ; G. Passalacqua [Italie] ; F. Portejoie [France] ; D. Price [Singapour] ; D. Ryan [Royaume-Uni] ; B. Samolinski [Pologne] ; A. Sheikh [Royaume-Uni] ; F E R. Simons [Canada] ; O. Spranger [Autriche] ; A. Todo Bom [Portugal] ; P V Tomazic [Autriche] ; M. Triggiani [Italie] ; A. Valero [Espagne] ; E. Valovirta [Finlande] ; A. Valiulis [Lituanie] ; M. Van Eerd [Pays-Bas] ; M. Wickman [Suède] ; I. Young [Royaume-Uni] ; T. Zuberbier [Allemagne]Source :
- Allergy [ 1398-9995 ] ; 2017.
Abstract
Allergic rhinitis often impairs social life and performance. The aim of this cross-sectional study was to use cell phone data to assess the impact on work productivity of uncontrolled rhinitis assessed by visual analogue scale (VAS). A mobile phone app (Allergy Diary, Google Play Store and Apple App Store) collects data from daily visual analogue scales (VAS) for overall allergic symptoms (VAS-global measured), nasal (VAS-nasal), ocular (VAS-ocular) and asthma symptoms (VAS-asthma) as well as work (VAS-work). A combined nasal-ocular score is calculated. The Allergy Diary is available in 21 countries. The app includes the Work Productivity and Activity Impairment Allergic Specific Questionnaire (WPAI:AS) in six EU countries. All consecutive users who completed the VAS-work from 1 June to 31 October 2016 were included in the study. A total of 1136 users filled in 5818 days of VAS-work. Symptoms of allergic rhinitis were controlled (VAS-global <20) in approximately 60% of the days. In users with uncontrolled rhinitis, approximately 90% had some work impairment and over 50% had severe work impairment (VAS-work >50). There was a significant correlation between VAS-global calculated and VAS-work (Rho=0.83, P<0.00001, Spearman's rank test). In 144 users, there was a significant correlation between VAS-work and WPAI:AS (Rho=0.53, P<0.0001). This pilot study provides not only proof-of-concept data on the work impairment collected with the app but also data on the app itself, especially the distribution of responses for the VAS. This supports the interpretation that persons with rhinitis report both the presence and the absence of symptoms.
DOI: 10.1111/all.13177
PubMed: 28387952
Affiliations:
- Allemagne, Australie, Autriche, Belgique, Brésil, Canada, Danemark, Espagne, Finlande, France, Irlande (pays), Italie, Lituanie, Mexique, Pays-Bas, Pologne, Portugal, Royaume-Uni, Singapour, Suède
- Angleterre, Bahia, Berlin, Catalogne, Finlande occidentale, Grand Londres, Grand Manchester, Hollande-Méridionale, Hollande-Septentrionale, Languedoc-Roussillon, Manitoba, Occitanie (région administrative), Svealand, Vienne (Autriche), Écosse, Île-de-France
- Amsterdam, Barcelone, Berlin, Leyde, Londres, Manchester, Montpellier, Paris, Rotterdam, Stockholm, Turku, Vienne (Autriche), Winnipeg, Édimbourg
- Université d'Édimbourg, Université de Barcelone, Université de Manchester, Université de Turku, Université du Manitoba
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Bousquet</name><affiliation wicri:level="3"><nlm:affiliation>MACVIA-France, Contre les MAladies Chroniques pour un VIeillissement Actif en France European Innovation Partnership on Active and Healthy Ageing Reference Site, Montpellier, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>MACVIA-France, Contre les MAladies Chroniques pour un VIeillissement Actif en France European Innovation Partnership on Active and Healthy Ageing Reference Site, Montpellier</wicri:regionArea><placeName><region type="region">Occitanie (région administrative)</region><region type="old region">Languedoc-Roussillon</region><settlement type="city">Montpellier</settlement></placeName></affiliation></author><author><name sortKey="Bewick, M" sort="Bewick, M" uniqKey="Bewick M" first="M" last="Bewick">M. 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Vandenplas</name><affiliation wicri:level="1"><nlm:affiliation>Department of Chest Medicine, Centre Hospitalier Universitaire UCL Namur, Université Catholique de Louvain, Yvoir, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Department of Chest Medicine, Centre Hospitalier Universitaire UCL Namur, Université Catholique de Louvain, Yvoir</wicri:regionArea><wicri:noRegion>Yvoir</wicri:noRegion></affiliation></author><author><name sortKey="Hellings, P W" sort="Hellings, P W" uniqKey="Hellings P" first="P W" last="Hellings">P W Hellings</name><affiliation wicri:level="1"><nlm:affiliation>Laboratory of Clinical Immunology, Department of Microbiology and Immunology, KU Leuven, Leuven, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Laboratory of Clinical Immunology, Department of Microbiology and Immunology, KU Leuven, Leuven</wicri:regionArea><wicri:noRegion>Leuven</wicri:noRegion></affiliation></author><author><name sortKey="Bachert, C" sort="Bachert, C" uniqKey="Bachert C" first="C" last="Bachert">C. 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Bindslev-Jensen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Dermatology and Allergy Centre, Odense University Hospital, Odense, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Dermatology and Allergy Centre, Odense University Hospital, Odense</wicri:regionArea><wicri:noRegion>Odense</wicri:noRegion></affiliation></author><author><name sortKey="Bosnic Anticevich, S" sort="Bosnic Anticevich, S" uniqKey="Bosnic Anticevich S" first="S" last="Bosnic-Anticevich">S. Bosnic-Anticevich</name><affiliation wicri:level="1"><nlm:affiliation>Woolcock Institute of Medical Research, University of Sydney and Sydney Local Health District, Glebe, NSW, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Woolcock Institute of Medical Research, University of Sydney and Sydney Local Health District, Glebe, NSW</wicri:regionArea><wicri:noRegion>NSW</wicri:noRegion></affiliation></author><author><name sortKey="Bouchard, J" sort="Bouchard, J" uniqKey="Bouchard J" first="J" last="Bouchard">J. Bouchard</name><affiliation wicri:level="1"><nlm:affiliation>Laval's Unit, Clinical Medicine, Quebec City, QC, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Laval's Unit, Clinical Medicine, Quebec City, QC</wicri:regionArea><wicri:noRegion>QC</wicri:noRegion></affiliation></author><author><name sortKey="Canonica, G W" sort="Canonica, G W" uniqKey="Canonica G" first="G W" last="Canonica">G W Canonica</name><affiliation wicri:level="1"><nlm:affiliation>Personalized Medicine Clinic Asthma & Allergy, Humanitas University, Humanitas Research Hospital, Rozzano, Milano, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Personalized Medicine Clinic Asthma & Allergy, Humanitas University, Humanitas Research Hospital, Rozzano, Milano</wicri:regionArea><wicri:noRegion>Milano</wicri:noRegion></affiliation></author><author><name sortKey="Chavannes, N H" sort="Chavannes, N H" uniqKey="Chavannes N" first="N H" last="Chavannes">N H Chavannes</name><affiliation wicri:level="3"><nlm:affiliation>Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Public Health and Primary Care, Leiden University Medical Center, Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Cruz, A A" sort="Cruz, A A" uniqKey="Cruz A" first="A A" last="Cruz">A A Cruz</name><affiliation wicri:level="2"><nlm:affiliation>ProAR - Nucleo de Excelencia em Asma, Federal University of Bahia, Bahia, Brazil.</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>ProAR - Nucleo de Excelencia em Asma, Federal University of Bahia, Bahia</wicri:regionArea><placeName><region type="state">Bahia</region></placeName></affiliation></author><author><name sortKey="Dahl, R" sort="Dahl, R" uniqKey="Dahl R" first="R" last="Dahl">R. Dahl</name><affiliation wicri:level="2"><nlm:affiliation>ProAR - Nucleo de Excelencia em Asma, Federal University of Bahia, Bahia, Brazil.</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>ProAR - Nucleo de Excelencia em Asma, Federal University of Bahia, Bahia</wicri:regionArea><placeName><region type="state">Bahia</region></placeName></affiliation></author><author><name sortKey="Demoly, P" sort="Demoly, P" uniqKey="Demoly P" first="P" last="Demoly">P. Demoly</name><affiliation wicri:level="3"><nlm:affiliation>Department of Respiratory Diseases, Montpellier University Hospital, Montpellier, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Respiratory Diseases, Montpellier University Hospital, Montpellier</wicri:regionArea><placeName><region type="region">Occitanie (région administrative)</region><region type="old region">Languedoc-Roussillon</region><settlement type="city">Montpellier</settlement></placeName></affiliation></author><author><name sortKey="De Vries, G" sort="De Vries, G" uniqKey="De Vries G" first="G" last="De Vries">G. De Vries</name><affiliation wicri:level="1"><nlm:affiliation>Peercode DV, Gerdermalsen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Peercode DV, Gerdermalsen</wicri:regionArea><wicri:noRegion>Gerdermalsen</wicri:noRegion></affiliation></author><author><name sortKey="Devillier, P" sort="Devillier, P" uniqKey="Devillier P" first="P" last="Devillier">P. Devillier</name><affiliation wicri:level="1"><nlm:affiliation>Laboratoire de Pharmacologie Respiratoire UPRES EA220, Pôle des Maladies Respiratoires, Hôpital Foch, Suresnes, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Laboratoire de Pharmacologie Respiratoire UPRES EA220, Pôle des Maladies Respiratoires, Hôpital Foch, Suresnes</wicri:regionArea><wicri:noRegion>Suresnes</wicri:noRegion><wicri:noRegion>Suresnes</wicri:noRegion></affiliation></author><author><name sortKey="Fink Wagner, A" sort="Fink Wagner, A" uniqKey="Fink Wagner A" first="A" last="Fink-Wagner">A. Fink-Wagner</name><affiliation wicri:level="3"><nlm:affiliation>Global Allergy and Asthma Platform GAAPP, Vienna, Austria.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Global Allergy and Asthma Platform GAAPP, Vienna</wicri:regionArea><placeName><settlement type="city">Vienne (Autriche)</settlement><region nuts="2" type="province">Vienne (Autriche)</region></placeName></affiliation></author><author><name sortKey="Fokkens, W J" sort="Fokkens, W J" uniqKey="Fokkens W" first="W J" last="Fokkens">W J Fokkens</name><affiliation wicri:level="3"><nlm:affiliation>Department of Otorhinolaryngology, Academic Medical Centre, Amsterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Otorhinolaryngology, Academic Medical Centre, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Fonseca, J" sort="Fonseca, J" uniqKey="Fonseca J" first="J" last="Fonseca">J. Fonseca</name><affiliation wicri:level="1"><nlm:affiliation>Center for Health Technology and Services Research- CINTESIS, Faculdade de Medicina, Universidade do Porto, Porto, Portugal.</nlm:affiliation><country xml:lang="fr">Portugal</country><wicri:regionArea>Center for Health Technology and Services Research- CINTESIS, Faculdade de Medicina, Universidade do Porto, Porto</wicri:regionArea><wicri:noRegion>Porto</wicri:noRegion></affiliation></author><author><name sortKey="Guldemond, N A" sort="Guldemond, N A" uniqKey="Guldemond N" first="N A" last="Guldemond">N A Guldemond</name><affiliation wicri:level="3"><nlm:affiliation>Institute of Health Policy and Management iBMG, Erasmus University, Rotterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Institute of Health Policy and Management iBMG, Erasmus University, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Haahtela, T" sort="Haahtela, T" uniqKey="Haahtela T" first="T" last="Haahtela">T. Haahtela</name><affiliation wicri:level="1"><nlm:affiliation>Skin and Allergy Hospital, Helsinki University Hospital, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Skin and Allergy Hospital, Helsinki University Hospital, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Hellqvist Dahl, B" sort="Hellqvist Dahl, B" uniqKey="Hellqvist Dahl B" first="B" last="Hellqvist-Dahl">B. Hellqvist-Dahl</name><affiliation wicri:level="1"><nlm:affiliation>Department of Respiratory Diseases, Odense University Hospital, Odense, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Respiratory Diseases, Odense University Hospital, Odense</wicri:regionArea><wicri:noRegion>Odense</wicri:noRegion></affiliation></author><author><name sortKey="Just, J" sort="Just, J" uniqKey="Just J" first="J" last="Just">J. Just</name><affiliation wicri:level="3"><nlm:affiliation>Allergology Department, Centre de l'Asthme et des Allergies. Hôpital d'Enfants Armand-Trousseau (APHP), Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Allergology Department, Centre de l'Asthme et des Allergies. Hôpital d'Enfants Armand-Trousseau (APHP), Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Keil, T" sort="Keil, T" uniqKey="Keil T" first="T" last="Keil">T. Keil</name><affiliation wicri:level="3"><nlm:affiliation>Institute of Social Medicine, Epidemiology and Health Economics, Charité - Universitätsmedizin Berlin, Berlin, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Social Medicine, Epidemiology and Health Economics, Charité - Universitätsmedizin Berlin, Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author><author><name sortKey="Klimek, L" sort="Klimek, L" uniqKey="Klimek L" first="L" last="Klimek">L. Klimek</name><affiliation wicri:level="1"><nlm:affiliation>Center for Rhinology and Allergology, Wiesbaden, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Center for Rhinology and Allergology, Wiesbaden</wicri:regionArea><wicri:noRegion>Wiesbaden</wicri:noRegion><wicri:noRegion>Wiesbaden</wicri:noRegion><wicri:noRegion>Wiesbaden</wicri:noRegion></affiliation></author><author><name sortKey="Kowalski, M L" sort="Kowalski, M L" uniqKey="Kowalski M" first="M L" last="Kowalski">M L Kowalski</name><affiliation wicri:level="1"><nlm:affiliation>Department of Immunology, Rheumatology and Allergy, Medical University of Lodz, Lodz, Poland.</nlm:affiliation><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Immunology, Rheumatology and Allergy, Medical University of Lodz, Lodz</wicri:regionArea><wicri:noRegion>Lodz</wicri:noRegion></affiliation></author><author><name sortKey="Kuna, P" sort="Kuna, P" uniqKey="Kuna P" first="P" last="Kuna">P. Kuna</name><affiliation wicri:level="1"><nlm:affiliation>Division of Internal Medicine, Asthma and Allergy, Barlicki University Hospital, Medical University of Lodz, Lodz, Poland.</nlm:affiliation><country xml:lang="fr">Pologne</country><wicri:regionArea>Division of Internal Medicine, Asthma and Allergy, Barlicki University Hospital, Medical University of Lodz, Lodz</wicri:regionArea><wicri:noRegion>Lodz</wicri:noRegion></affiliation></author><author><name sortKey="Kvedariene, V" sort="Kvedariene, V" uniqKey="Kvedariene V" first="V" last="Kvedariene">V. Kvedariene</name><affiliation wicri:level="1"><nlm:affiliation>Clinic of Infectious, Chest Diseases, Dermatology and Allergology, Vilnius University, Vilnius, Lithuania.</nlm:affiliation><country xml:lang="fr">Lituanie</country><wicri:regionArea>Clinic of Infectious, Chest Diseases, Dermatology and Allergology, Vilnius University, Vilnius</wicri:regionArea><wicri:noRegion>Vilnius</wicri:noRegion></affiliation></author><author><name sortKey="Laune, D" sort="Laune, D" uniqKey="Laune D" first="D" last="Laune">D. Laune</name><affiliation wicri:level="3"><nlm:affiliation>Kyomed, Montpellier, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Kyomed, Montpellier</wicri:regionArea><placeName><region type="region">Occitanie (région administrative)</region><region type="old region">Languedoc-Roussillon</region><settlement type="city">Montpellier</settlement></placeName></affiliation></author><author><name sortKey="Larenas Linnemann, D" sort="Larenas Linnemann, D" uniqKey="Larenas Linnemann D" first="D" last="Larenas-Linnemann">D. Larenas-Linnemann</name><affiliation wicri:level="1"><nlm:affiliation>Clínica de Alergia, Asma y Pediatría, Hospital Médica Sur, México City, Mexico.</nlm:affiliation><country xml:lang="fr">Mexique</country><wicri:regionArea>Clínica de Alergia, Asma y Pediatría, Hospital Médica Sur, México City</wicri:regionArea><wicri:noRegion>México City</wicri:noRegion></affiliation></author><author><name sortKey="Mullol, J" sort="Mullol, J" uniqKey="Mullol J" first="J" last="Mullol">J. Mullol</name><affiliation wicri:level="4"><nlm:affiliation>Clinical & Experimental Respiratory Immunoallergy, ENT Department, Hospital Clínic, IDIBAPS, Universitat de Barcelona, Barcelona, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Clinical & Experimental Respiratory Immunoallergy, ENT Department, Hospital Clínic, IDIBAPS, Universitat de Barcelona, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region><settlement type="city">Barcelone</settlement></placeName><orgName type="university">Université de Barcelone</orgName></affiliation></author><author><name sortKey="Pereira, A M" sort="Pereira, A M" uniqKey="Pereira A" first="A M" last="Pereira">A M Pereira</name><affiliation wicri:level="1"><nlm:affiliation>Immunoallergy Department, CUF-Descobertas Hospital, Lisbon, Portugal.</nlm:affiliation><country xml:lang="fr">Portugal</country><wicri:regionArea>Immunoallergy Department, CUF-Descobertas Hospital, Lisbon</wicri:regionArea><wicri:noRegion>Lisbon</wicri:noRegion></affiliation></author><author><name sortKey="Carreiro Martins, P" sort="Carreiro Martins, P" uniqKey="Carreiro Martins P" first="P" last="Carreiro-Martins">P. Carreiro-Martins</name><affiliation wicri:level="1"><nlm:affiliation>CEDOC, Respiratory Research Group, Nova Medical School, Campo dos Martires da Patria, Lisbon, Portugal.</nlm:affiliation><country xml:lang="fr">Portugal</country><wicri:regionArea>CEDOC, Respiratory Research Group, Nova Medical School, Campo dos Martires da Patria, Lisbon</wicri:regionArea><wicri:noRegion>Lisbon</wicri:noRegion></affiliation></author><author><name sortKey="Melen, E" sort="Melen, E" uniqKey="Melen E" first="E" last="Melén">E. Melén</name><affiliation wicri:level="3"><nlm:affiliation>Sachs' Children and Youth Hospital, Södersjukhuset, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Sachs' Children and Youth Hospital, Södersjukhuset, Institute of Environmental Medicine, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Morais Almeida, M" sort="Morais Almeida, M" uniqKey="Morais Almeida M" first="M" last="Morais-Almeida">M. Morais-Almeida</name><affiliation wicri:level="1"><nlm:affiliation>Allergy and Clinical Immunology Department, Hospital CUF-Descobertas, Lisboa, Portugal.</nlm:affiliation><country xml:lang="fr">Portugal</country><wicri:regionArea>Allergy and Clinical Immunology Department, Hospital CUF-Descobertas, Lisboa</wicri:regionArea><wicri:noRegion>Lisboa</wicri:noRegion></affiliation></author><author><name sortKey="Nogueira Silva, L" sort="Nogueira Silva, L" uniqKey="Nogueira Silva L" first="L" last="Nogueira-Silva">L. Nogueira-Silva</name><affiliation wicri:level="1"><nlm:affiliation>Center for Health Technology and Services Research - CINTESIS and Department of Internal Medicine, Centro Hospitalar Sao Joao, Porto, Portugal.</nlm:affiliation><country xml:lang="fr">Portugal</country><wicri:regionArea>Center for Health Technology and Services Research - CINTESIS and Department of Internal Medicine, Centro Hospitalar Sao Joao, Porto</wicri:regionArea><wicri:noRegion>Porto</wicri:noRegion></affiliation></author><author><name sortKey="O Hehir, R E" sort="O Hehir, R E" uniqKey="O Hehir R" first="R E" last="O'Hehir">R E O'Hehir</name><affiliation wicri:level="1"><nlm:affiliation>Department of Allergy, Immunology and Respiratory Medicine, Alfred Hospital and Central Clinical School, Monash University, Melbourne, Vic., Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Allergy, Immunology and Respiratory Medicine, Alfred Hospital and Central Clinical School, Monash University, Melbourne, Vic.</wicri:regionArea><wicri:noRegion>Vic.</wicri:noRegion></affiliation></author><author><name sortKey="Papadopoulos, N G" sort="Papadopoulos, N G" uniqKey="Papadopoulos N" first="N G" last="Papadopoulos">N G Papadopoulos</name><affiliation wicri:level="4"><nlm:affiliation>Center for Pediatrics and Child Health, Institute of Human Development, Royal Manchester Children's Hospital, University of Manchester, Manchester, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Center for Pediatrics and Child Health, Institute of Human Development, Royal Manchester Children's Hospital, University of Manchester, Manchester</wicri:regionArea><placeName><settlement type="city">Manchester</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Manchester</region><settlement type="city">Manchester</settlement></placeName><orgName type="university">Université de Manchester</orgName></affiliation></author><author><name sortKey="Passalacqua, G" sort="Passalacqua, G" uniqKey="Passalacqua G" first="G" last="Passalacqua">G. Passalacqua</name><affiliation wicri:level="1"><nlm:affiliation>Allergy and Respiratory Diseases, IRCCS San Martino-IST-University, Genoa, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Allergy and Respiratory Diseases, IRCCS San Martino-IST-University, Genoa</wicri:regionArea><wicri:noRegion>Genoa</wicri:noRegion></affiliation></author><author><name sortKey="Portejoie, F" sort="Portejoie, F" uniqKey="Portejoie F" first="F" last="Portejoie">F. Portejoie</name><affiliation wicri:level="3"><nlm:affiliation>MACVIA-France, Contre les MAladies Chroniques pour un VIeillissement Actif en France European Innovation Partnership on Active and Healthy Ageing Reference Site, Montpellier, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>MACVIA-France, Contre les MAladies Chroniques pour un VIeillissement Actif en France European Innovation Partnership on Active and Healthy Ageing Reference Site, Montpellier</wicri:regionArea><placeName><region type="region">Occitanie (région administrative)</region><region type="old region">Languedoc-Roussillon</region><settlement type="city">Montpellier</settlement></placeName></affiliation></author><author><name sortKey="Price, D" sort="Price, D" uniqKey="Price D" first="D" last="Price">D. Price</name><affiliation wicri:level="1"><nlm:affiliation>Observational and Pragmatic Research Institute, Singapore City, Singapore.</nlm:affiliation><country xml:lang="fr">Singapour</country><wicri:regionArea>Observational and Pragmatic Research Institute, Singapore City</wicri:regionArea><wicri:noRegion>Singapore City</wicri:noRegion></affiliation></author><author><name sortKey="Ryan, D" sort="Ryan, D" uniqKey="Ryan D" first="D" last="Ryan">D. Ryan</name><affiliation wicri:level="4"><nlm:affiliation>Allergy and Respiratory Research Group, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Allergy and Respiratory Research Group, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation></author><author><name sortKey="Samolinski, B" sort="Samolinski, B" uniqKey="Samolinski B" first="B" last="Samolinski">B. Samolinski</name><affiliation wicri:level="1"><nlm:affiliation>Department of Prevention of Environmental Hazards and Allergology, Medical University of Warsaw, Warsaw, Poland.</nlm:affiliation><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Prevention of Environmental Hazards and Allergology, Medical University of Warsaw, Warsaw</wicri:regionArea><wicri:noRegion>Warsaw</wicri:noRegion></affiliation></author><author><name sortKey="Sheikh, A" sort="Sheikh, A" uniqKey="Sheikh A" first="A" last="Sheikh">A. Sheikh</name><affiliation wicri:level="4"><nlm:affiliation>Centre of Medical Informatics, Usher Institute of Population Health Sciences and Informatics, The University of Edinburgh, Edinburgh, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre of Medical Informatics, Usher Institute of Population Health Sciences and Informatics, The University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation></author><author><name sortKey="Simons, F E R" sort="Simons, F E R" uniqKey="Simons F" first="F E R" last="Simons">F E R. Simons</name><affiliation wicri:level="4"><nlm:affiliation>Departments of Pediatrics & Child Health and Immunology, Faculty of Medicine, University of Manitoba, Winnipeg, MB, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Departments of Pediatrics & Child Health and Immunology, Faculty of Medicine, University of Manitoba, Winnipeg, MB</wicri:regionArea><orgName type="university">Université du Manitoba</orgName><placeName><settlement type="city">Winnipeg</settlement><region type="state">Manitoba</region></placeName></affiliation></author><author><name sortKey="Spranger, O" sort="Spranger, O" uniqKey="Spranger O" first="O" last="Spranger">O. Spranger</name><affiliation wicri:level="3"><nlm:affiliation>Global Allergy and Asthma Platform GAAPP, Vienna, Austria.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Global Allergy and Asthma Platform GAAPP, Vienna</wicri:regionArea><placeName><settlement type="city">Vienne (Autriche)</settlement><region nuts="2" type="province">Vienne (Autriche)</region></placeName></affiliation></author><author><name sortKey="Todo Bom, A" sort="Todo Bom, A" uniqKey="Todo Bom A" first="A" last="Todo Bom">A. Todo Bom</name><affiliation wicri:level="1"><nlm:affiliation>Imunoalergologia, Centro Hospitalar Universitário de Coimbra and Faculty of Medicine, University of Coimbra, Coimbra, Portugal.</nlm:affiliation><country xml:lang="fr">Portugal</country><wicri:regionArea>Imunoalergologia, Centro Hospitalar Universitário de Coimbra and Faculty of Medicine, University of Coimbra, Coimbra</wicri:regionArea><wicri:noRegion>Coimbra</wicri:noRegion></affiliation></author><author><name sortKey="Tomazic, P V" sort="Tomazic, P V" uniqKey="Tomazic P" first="P V" last="Tomazic">P V Tomazic</name><affiliation wicri:level="1"><nlm:affiliation>Department of ENT, Medical University of Graz, Graz, Austria.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Department of ENT, Medical University of Graz, Graz</wicri:regionArea><wicri:noRegion>Graz</wicri:noRegion></affiliation></author><author><name sortKey="Triggiani, M" sort="Triggiani, M" uniqKey="Triggiani M" first="M" last="Triggiani">M. Triggiani</name><affiliation wicri:level="1"><nlm:affiliation>Division of Allergy and Clinical Immunology, University of Salerno, Salerno, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Division of Allergy and Clinical Immunology, University of Salerno, Salerno</wicri:regionArea><wicri:noRegion>Salerno</wicri:noRegion></affiliation></author><author><name sortKey="Valero, A" sort="Valero, A" uniqKey="Valero A" first="A" last="Valero">A. Valero</name><affiliation wicri:level="3"><nlm:affiliation>Pneumology and Allergy Department, Ciberres and Clinical & Experimental Respiratory Imunoallergy, IDIBAPS, Universitat Barcelona, Barcelona, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Pneumology and Allergy Department, Ciberres and Clinical & Experimental Respiratory Imunoallergy, IDIBAPS, Universitat Barcelona, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Valovirta, E" sort="Valovirta, E" uniqKey="Valovirta E" first="E" last="Valovirta">E. Valovirta</name><affiliation wicri:level="4"><nlm:affiliation>Department of Lung Diseases and Clinical Immunology, University of Turku, Turku, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Lung Diseases and Clinical Immunology, University of Turku, Turku</wicri:regionArea><placeName><settlement type="city">Turku</settlement><region type="région" nuts="2">Finlande occidentale</region><settlement type="city">Turku</settlement></placeName><orgName type="university">Université de Turku</orgName></affiliation></author><author><name sortKey="Valiulis, A" sort="Valiulis, A" uniqKey="Valiulis A" first="A" last="Valiulis">A. Valiulis</name><affiliation wicri:level="1"><nlm:affiliation>Vilnius University Clinic of Children's Diseases and Public Health Institute, Vilnius, Lithuania.</nlm:affiliation><country xml:lang="fr">Lituanie</country><wicri:regionArea>Vilnius University Clinic of Children's Diseases and Public Health Institute, Vilnius</wicri:regionArea><wicri:noRegion>Vilnius</wicri:noRegion></affiliation></author><author><name sortKey="Van Eerd, M" sort="Van Eerd, M" uniqKey="Van Eerd M" first="M" last="Van Eerd">M. Van Eerd</name><affiliation wicri:level="1"><nlm:affiliation>Peercode DV, Gerdermalsen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Peercode DV, Gerdermalsen</wicri:regionArea><wicri:noRegion>Gerdermalsen</wicri:noRegion></affiliation></author><author><name sortKey="Wickman, M" sort="Wickman, M" uniqKey="Wickman M" first="M" last="Wickman">M. Wickman</name><affiliation wicri:level="3"><nlm:affiliation>Sachs' Children and Youth Hospital, Södersjukhuset, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Sachs' Children and Youth Hospital, Södersjukhuset, Institute of Environmental Medicine, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Young, I" sort="Young, I" uniqKey="Young I" first="I" last="Young">I. Young</name><affiliation wicri:level="1"><nlm:affiliation>Queen's University Belfast, Belfast, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Queen's University Belfast, Belfast</wicri:regionArea><wicri:noRegion>Belfast</wicri:noRegion></affiliation></author><author><name sortKey="Zuberbier, T" sort="Zuberbier, T" uniqKey="Zuberbier T" first="T" last="Zuberbier">T. Zuberbier</name><affiliation wicri:level="3"><nlm:affiliation>Global Allergy and Asthma European Network (GA2LEN), Comprehensive Allergy-Centre-Charité, Department of Dermatology and Allergy, Charité - Universitätsmedizin Berlin, Berlin, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Global Allergy and Asthma European Network (GA2LEN), Comprehensive Allergy-Centre-Charité, Department of Dermatology and Allergy, Charité - Universitätsmedizin Berlin, Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2017">2017</date><idno type="RBID">pubmed:28387952</idno><idno type="pmid">28387952</idno><idno type="doi">10.1111/all.13177</idno><idno type="wicri:Area/PubMed/Corpus">000440</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000440</idno><idno type="wicri:Area/PubMed/Curation">000438</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000438</idno><idno type="wicri:Area/PubMed/Checkpoint">000438</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000438</idno><idno type="wicri:Area/Ncbi/Merge">004605</idno><idno type="wicri:Area/Ncbi/Curation">004605</idno><idno type="wicri:Area/Ncbi/Checkpoint">004605</idno><idno type="wicri:Area/Main/Merge">000032</idno><idno type="wicri:Area/Main/Curation">000037</idno><idno type="wicri:Area/Main/Exploration">000037</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Work productivity in rhinitis using cell phones: The MASK pilot study.</title><author><name sortKey="Bousquet, J" sort="Bousquet, J" uniqKey="Bousquet J" first="J" last="Bousquet">J. Bousquet</name><affiliation wicri:level="3"><nlm:affiliation>MACVIA-France, Contre les MAladies Chroniques pour un VIeillissement Actif en France European Innovation Partnership on Active and Healthy Ageing Reference Site, Montpellier, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>MACVIA-France, Contre les MAladies Chroniques pour un VIeillissement Actif en France European Innovation Partnership on Active and Healthy Ageing Reference Site, Montpellier</wicri:regionArea><placeName><region type="region">Occitanie (région administrative)</region><region type="old region">Languedoc-Roussillon</region><settlement type="city">Montpellier</settlement></placeName></affiliation></author><author><name sortKey="Bewick, M" sort="Bewick, M" uniqKey="Bewick M" first="M" last="Bewick">M. Bewick</name><affiliation wicri:level="3"><nlm:affiliation>iQ4U Consultants Ltd, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>iQ4U Consultants Ltd, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Arnavielhe, S" sort="Arnavielhe, S" uniqKey="Arnavielhe S" first="S" last="Arnavielhe">S. Arnavielhe</name><affiliation wicri:level="3"><nlm:affiliation>Kyomed, Montpellier, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Kyomed, Montpellier</wicri:regionArea><placeName><region type="region">Occitanie (région administrative)</region><region type="old region">Languedoc-Roussillon</region><settlement type="city">Montpellier</settlement></placeName></affiliation></author><author><name sortKey="Mathieu Dupas, E" sort="Mathieu Dupas, E" uniqKey="Mathieu Dupas E" first="E" last="Mathieu-Dupas">E. Mathieu-Dupas</name><affiliation wicri:level="3"><nlm:affiliation>Kyomed, Montpellier, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Kyomed, Montpellier</wicri:regionArea><placeName><region type="region">Occitanie (région administrative)</region><region type="old region">Languedoc-Roussillon</region><settlement type="city">Montpellier</settlement></placeName></affiliation></author><author><name sortKey="Murray, R" sort="Murray, R" uniqKey="Murray R" first="R" last="Murray">R. Murray</name><affiliation wicri:level="1"><nlm:affiliation>Medical Communications Consultant, MedScript Ltd, Dundalk, Co. Louth, Ireland.</nlm:affiliation><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>Medical Communications Consultant, MedScript Ltd, Dundalk, Co. Louth</wicri:regionArea><wicri:noRegion>Co. Louth</wicri:noRegion></affiliation></author><author><name sortKey="Bedbrook, A" sort="Bedbrook, A" uniqKey="Bedbrook A" first="A" last="Bedbrook">A. Bedbrook</name><affiliation wicri:level="3"><nlm:affiliation>MACVIA-France, Contre les MAladies Chroniques pour un VIeillissement Actif en France European Innovation Partnership on Active and Healthy Ageing Reference Site, Montpellier, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>MACVIA-France, Contre les MAladies Chroniques pour un VIeillissement Actif en France European Innovation Partnership on Active and Healthy Ageing Reference Site, Montpellier</wicri:regionArea><placeName><region type="region">Occitanie (région administrative)</region><region type="old region">Languedoc-Roussillon</region><settlement type="city">Montpellier</settlement></placeName></affiliation></author><author><name sortKey="Caimmi, D P" sort="Caimmi, D P" uniqKey="Caimmi D" first="D P" last="Caimmi">D P Caimmi</name><affiliation wicri:level="3"><nlm:affiliation>Sorbonne Universités, UPMC Paris 06, UMR-S 1136, IPLESP, Equipe EPAR, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Sorbonne Universités, UPMC Paris 06, UMR-S 1136, IPLESP, Equipe EPAR, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Vandenplas, O" sort="Vandenplas, O" uniqKey="Vandenplas O" first="O" last="Vandenplas">O. Vandenplas</name><affiliation wicri:level="1"><nlm:affiliation>Department of Chest Medicine, Centre Hospitalier Universitaire UCL Namur, Université Catholique de Louvain, Yvoir, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Department of Chest Medicine, Centre Hospitalier Universitaire UCL Namur, Université Catholique de Louvain, Yvoir</wicri:regionArea><wicri:noRegion>Yvoir</wicri:noRegion></affiliation></author><author><name sortKey="Hellings, P W" sort="Hellings, P W" uniqKey="Hellings P" first="P W" last="Hellings">P W Hellings</name><affiliation wicri:level="1"><nlm:affiliation>Laboratory of Clinical Immunology, Department of Microbiology and Immunology, KU Leuven, Leuven, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Laboratory of Clinical Immunology, Department of Microbiology and Immunology, KU Leuven, Leuven</wicri:regionArea><wicri:noRegion>Leuven</wicri:noRegion></affiliation></author><author><name sortKey="Bachert, C" sort="Bachert, C" uniqKey="Bachert C" first="C" last="Bachert">C. Bachert</name><affiliation wicri:level="1"><nlm:affiliation>Upper Airways Research Laboratory, ENT Department, Ghent University Hospital, Ghent, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Upper Airways Research Laboratory, ENT Department, Ghent University Hospital, Ghent</wicri:regionArea><wicri:noRegion>Ghent</wicri:noRegion></affiliation></author><author><name sortKey="Anto, J M" sort="Anto, J M" uniqKey="Anto J" first="J M" last="Anto">J M Anto</name><affiliation wicri:level="3"><nlm:affiliation>ISGLoBAL, Centre for Research in Environmental Epidemiology (CREAL), IMIM (Hospital del Mar Research Institute), CIBER Epidemiología y Salud Pública (CIBERESP) & Universitat Pompeu Fabra (UPF), Barcelona, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>ISGLoBAL, Centre for Research in Environmental Epidemiology (CREAL), IMIM (Hospital del Mar Research Institute), CIBER Epidemiología y Salud Pública (CIBERESP) & Universitat Pompeu Fabra (UPF), Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Bergmann, K C" sort="Bergmann, K C" uniqKey="Bergmann K" first="K C" last="Bergmann">K C Bergmann</name><affiliation wicri:level="3"><nlm:affiliation>Global Allergy and Asthma European Network (GA2LEN), Comprehensive Allergy-Centre-Charité, Department of Dermatology and Allergy, Charité - Universitätsmedizin Berlin, Berlin, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Global Allergy and Asthma European Network (GA2LEN), Comprehensive Allergy-Centre-Charité, Department of Dermatology and Allergy, Charité - Universitätsmedizin Berlin, Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author><author><name sortKey="Bindslev Jensen, C" sort="Bindslev Jensen, C" uniqKey="Bindslev Jensen C" first="C" last="Bindslev-Jensen">C. Bindslev-Jensen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Dermatology and Allergy Centre, Odense University Hospital, Odense, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Dermatology and Allergy Centre, Odense University Hospital, Odense</wicri:regionArea><wicri:noRegion>Odense</wicri:noRegion></affiliation></author><author><name sortKey="Bosnic Anticevich, S" sort="Bosnic Anticevich, S" uniqKey="Bosnic Anticevich S" first="S" last="Bosnic-Anticevich">S. Bosnic-Anticevich</name><affiliation wicri:level="1"><nlm:affiliation>Woolcock Institute of Medical Research, University of Sydney and Sydney Local Health District, Glebe, NSW, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Woolcock Institute of Medical Research, University of Sydney and Sydney Local Health District, Glebe, NSW</wicri:regionArea><wicri:noRegion>NSW</wicri:noRegion></affiliation></author><author><name sortKey="Bouchard, J" sort="Bouchard, J" uniqKey="Bouchard J" first="J" last="Bouchard">J. Bouchard</name><affiliation wicri:level="1"><nlm:affiliation>Laval's Unit, Clinical Medicine, Quebec City, QC, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Laval's Unit, Clinical Medicine, Quebec City, QC</wicri:regionArea><wicri:noRegion>QC</wicri:noRegion></affiliation></author><author><name sortKey="Canonica, G W" sort="Canonica, G W" uniqKey="Canonica G" first="G W" last="Canonica">G W Canonica</name><affiliation wicri:level="1"><nlm:affiliation>Personalized Medicine Clinic Asthma & Allergy, Humanitas University, Humanitas Research Hospital, Rozzano, Milano, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Personalized Medicine Clinic Asthma & Allergy, Humanitas University, Humanitas Research Hospital, Rozzano, Milano</wicri:regionArea><wicri:noRegion>Milano</wicri:noRegion></affiliation></author><author><name sortKey="Chavannes, N H" sort="Chavannes, N H" uniqKey="Chavannes N" first="N H" last="Chavannes">N H Chavannes</name><affiliation wicri:level="3"><nlm:affiliation>Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Public Health and Primary Care, Leiden University Medical Center, Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Cruz, A A" sort="Cruz, A A" uniqKey="Cruz A" first="A A" last="Cruz">A A Cruz</name><affiliation wicri:level="2"><nlm:affiliation>ProAR - Nucleo de Excelencia em Asma, Federal University of Bahia, Bahia, Brazil.</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>ProAR - Nucleo de Excelencia em Asma, Federal University of Bahia, Bahia</wicri:regionArea><placeName><region type="state">Bahia</region></placeName></affiliation></author><author><name sortKey="Dahl, R" sort="Dahl, R" uniqKey="Dahl R" first="R" last="Dahl">R. Dahl</name><affiliation wicri:level="2"><nlm:affiliation>ProAR - Nucleo de Excelencia em Asma, Federal University of Bahia, Bahia, Brazil.</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>ProAR - Nucleo de Excelencia em Asma, Federal University of Bahia, Bahia</wicri:regionArea><placeName><region type="state">Bahia</region></placeName></affiliation></author><author><name sortKey="Demoly, P" sort="Demoly, P" uniqKey="Demoly P" first="P" last="Demoly">P. Demoly</name><affiliation wicri:level="3"><nlm:affiliation>Department of Respiratory Diseases, Montpellier University Hospital, Montpellier, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Respiratory Diseases, Montpellier University Hospital, Montpellier</wicri:regionArea><placeName><region type="region">Occitanie (région administrative)</region><region type="old region">Languedoc-Roussillon</region><settlement type="city">Montpellier</settlement></placeName></affiliation></author><author><name sortKey="De Vries, G" sort="De Vries, G" uniqKey="De Vries G" first="G" last="De Vries">G. De Vries</name><affiliation wicri:level="1"><nlm:affiliation>Peercode DV, Gerdermalsen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Peercode DV, Gerdermalsen</wicri:regionArea><wicri:noRegion>Gerdermalsen</wicri:noRegion></affiliation></author><author><name sortKey="Devillier, P" sort="Devillier, P" uniqKey="Devillier P" first="P" last="Devillier">P. Devillier</name><affiliation wicri:level="1"><nlm:affiliation>Laboratoire de Pharmacologie Respiratoire UPRES EA220, Pôle des Maladies Respiratoires, Hôpital Foch, Suresnes, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Laboratoire de Pharmacologie Respiratoire UPRES EA220, Pôle des Maladies Respiratoires, Hôpital Foch, Suresnes</wicri:regionArea><wicri:noRegion>Suresnes</wicri:noRegion><wicri:noRegion>Suresnes</wicri:noRegion></affiliation></author><author><name sortKey="Fink Wagner, A" sort="Fink Wagner, A" uniqKey="Fink Wagner A" first="A" last="Fink-Wagner">A. Fink-Wagner</name><affiliation wicri:level="3"><nlm:affiliation>Global Allergy and Asthma Platform GAAPP, Vienna, Austria.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Global Allergy and Asthma Platform GAAPP, Vienna</wicri:regionArea><placeName><settlement type="city">Vienne (Autriche)</settlement><region nuts="2" type="province">Vienne (Autriche)</region></placeName></affiliation></author><author><name sortKey="Fokkens, W J" sort="Fokkens, W J" uniqKey="Fokkens W" first="W J" last="Fokkens">W J Fokkens</name><affiliation wicri:level="3"><nlm:affiliation>Department of Otorhinolaryngology, Academic Medical Centre, Amsterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Otorhinolaryngology, Academic Medical Centre, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Fonseca, J" sort="Fonseca, J" uniqKey="Fonseca J" first="J" last="Fonseca">J. Fonseca</name><affiliation wicri:level="1"><nlm:affiliation>Center for Health Technology and Services Research- CINTESIS, Faculdade de Medicina, Universidade do Porto, Porto, Portugal.</nlm:affiliation><country xml:lang="fr">Portugal</country><wicri:regionArea>Center for Health Technology and Services Research- CINTESIS, Faculdade de Medicina, Universidade do Porto, Porto</wicri:regionArea><wicri:noRegion>Porto</wicri:noRegion></affiliation></author><author><name sortKey="Guldemond, N A" sort="Guldemond, N A" uniqKey="Guldemond N" first="N A" last="Guldemond">N A Guldemond</name><affiliation wicri:level="3"><nlm:affiliation>Institute of Health Policy and Management iBMG, Erasmus University, Rotterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Institute of Health Policy and Management iBMG, Erasmus University, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Haahtela, T" sort="Haahtela, T" uniqKey="Haahtela T" first="T" last="Haahtela">T. Haahtela</name><affiliation wicri:level="1"><nlm:affiliation>Skin and Allergy Hospital, Helsinki University Hospital, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Skin and Allergy Hospital, Helsinki University Hospital, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Hellqvist Dahl, B" sort="Hellqvist Dahl, B" uniqKey="Hellqvist Dahl B" first="B" last="Hellqvist-Dahl">B. Hellqvist-Dahl</name><affiliation wicri:level="1"><nlm:affiliation>Department of Respiratory Diseases, Odense University Hospital, Odense, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Respiratory Diseases, Odense University Hospital, Odense</wicri:regionArea><wicri:noRegion>Odense</wicri:noRegion></affiliation></author><author><name sortKey="Just, J" sort="Just, J" uniqKey="Just J" first="J" last="Just">J. Just</name><affiliation wicri:level="3"><nlm:affiliation>Allergology Department, Centre de l'Asthme et des Allergies. Hôpital d'Enfants Armand-Trousseau (APHP), Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Allergology Department, Centre de l'Asthme et des Allergies. Hôpital d'Enfants Armand-Trousseau (APHP), Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Keil, T" sort="Keil, T" uniqKey="Keil T" first="T" last="Keil">T. Keil</name><affiliation wicri:level="3"><nlm:affiliation>Institute of Social Medicine, Epidemiology and Health Economics, Charité - Universitätsmedizin Berlin, Berlin, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Social Medicine, Epidemiology and Health Economics, Charité - Universitätsmedizin Berlin, Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author><author><name sortKey="Klimek, L" sort="Klimek, L" uniqKey="Klimek L" first="L" last="Klimek">L. Klimek</name><affiliation wicri:level="1"><nlm:affiliation>Center for Rhinology and Allergology, Wiesbaden, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Center for Rhinology and Allergology, Wiesbaden</wicri:regionArea><wicri:noRegion>Wiesbaden</wicri:noRegion><wicri:noRegion>Wiesbaden</wicri:noRegion><wicri:noRegion>Wiesbaden</wicri:noRegion></affiliation></author><author><name sortKey="Kowalski, M L" sort="Kowalski, M L" uniqKey="Kowalski M" first="M L" last="Kowalski">M L Kowalski</name><affiliation wicri:level="1"><nlm:affiliation>Department of Immunology, Rheumatology and Allergy, Medical University of Lodz, Lodz, Poland.</nlm:affiliation><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Immunology, Rheumatology and Allergy, Medical University of Lodz, Lodz</wicri:regionArea><wicri:noRegion>Lodz</wicri:noRegion></affiliation></author><author><name sortKey="Kuna, P" sort="Kuna, P" uniqKey="Kuna P" first="P" last="Kuna">P. Kuna</name><affiliation wicri:level="1"><nlm:affiliation>Division of Internal Medicine, Asthma and Allergy, Barlicki University Hospital, Medical University of Lodz, Lodz, Poland.</nlm:affiliation><country xml:lang="fr">Pologne</country><wicri:regionArea>Division of Internal Medicine, Asthma and Allergy, Barlicki University Hospital, Medical University of Lodz, Lodz</wicri:regionArea><wicri:noRegion>Lodz</wicri:noRegion></affiliation></author><author><name sortKey="Kvedariene, V" sort="Kvedariene, V" uniqKey="Kvedariene V" first="V" last="Kvedariene">V. Kvedariene</name><affiliation wicri:level="1"><nlm:affiliation>Clinic of Infectious, Chest Diseases, Dermatology and Allergology, Vilnius University, Vilnius, Lithuania.</nlm:affiliation><country xml:lang="fr">Lituanie</country><wicri:regionArea>Clinic of Infectious, Chest Diseases, Dermatology and Allergology, Vilnius University, Vilnius</wicri:regionArea><wicri:noRegion>Vilnius</wicri:noRegion></affiliation></author><author><name sortKey="Laune, D" sort="Laune, D" uniqKey="Laune D" first="D" last="Laune">D. Laune</name><affiliation wicri:level="3"><nlm:affiliation>Kyomed, Montpellier, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Kyomed, Montpellier</wicri:regionArea><placeName><region type="region">Occitanie (région administrative)</region><region type="old region">Languedoc-Roussillon</region><settlement type="city">Montpellier</settlement></placeName></affiliation></author><author><name sortKey="Larenas Linnemann, D" sort="Larenas Linnemann, D" uniqKey="Larenas Linnemann D" first="D" last="Larenas-Linnemann">D. Larenas-Linnemann</name><affiliation wicri:level="1"><nlm:affiliation>Clínica de Alergia, Asma y Pediatría, Hospital Médica Sur, México City, Mexico.</nlm:affiliation><country xml:lang="fr">Mexique</country><wicri:regionArea>Clínica de Alergia, Asma y Pediatría, Hospital Médica Sur, México City</wicri:regionArea><wicri:noRegion>México City</wicri:noRegion></affiliation></author><author><name sortKey="Mullol, J" sort="Mullol, J" uniqKey="Mullol J" first="J" last="Mullol">J. Mullol</name><affiliation wicri:level="4"><nlm:affiliation>Clinical & Experimental Respiratory Immunoallergy, ENT Department, Hospital Clínic, IDIBAPS, Universitat de Barcelona, Barcelona, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Clinical & Experimental Respiratory Immunoallergy, ENT Department, Hospital Clínic, IDIBAPS, Universitat de Barcelona, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region><settlement type="city">Barcelone</settlement></placeName><orgName type="university">Université de Barcelone</orgName></affiliation></author><author><name sortKey="Pereira, A M" sort="Pereira, A M" uniqKey="Pereira A" first="A M" last="Pereira">A M Pereira</name><affiliation wicri:level="1"><nlm:affiliation>Immunoallergy Department, CUF-Descobertas Hospital, Lisbon, Portugal.</nlm:affiliation><country xml:lang="fr">Portugal</country><wicri:regionArea>Immunoallergy Department, CUF-Descobertas Hospital, Lisbon</wicri:regionArea><wicri:noRegion>Lisbon</wicri:noRegion></affiliation></author><author><name sortKey="Carreiro Martins, P" sort="Carreiro Martins, P" uniqKey="Carreiro Martins P" first="P" last="Carreiro-Martins">P. Carreiro-Martins</name><affiliation wicri:level="1"><nlm:affiliation>CEDOC, Respiratory Research Group, Nova Medical School, Campo dos Martires da Patria, Lisbon, Portugal.</nlm:affiliation><country xml:lang="fr">Portugal</country><wicri:regionArea>CEDOC, Respiratory Research Group, Nova Medical School, Campo dos Martires da Patria, Lisbon</wicri:regionArea><wicri:noRegion>Lisbon</wicri:noRegion></affiliation></author><author><name sortKey="Melen, E" sort="Melen, E" uniqKey="Melen E" first="E" last="Melén">E. Melén</name><affiliation wicri:level="3"><nlm:affiliation>Sachs' Children and Youth Hospital, Södersjukhuset, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Sachs' Children and Youth Hospital, Södersjukhuset, Institute of Environmental Medicine, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Morais Almeida, M" sort="Morais Almeida, M" uniqKey="Morais Almeida M" first="M" last="Morais-Almeida">M. Morais-Almeida</name><affiliation wicri:level="1"><nlm:affiliation>Allergy and Clinical Immunology Department, Hospital CUF-Descobertas, Lisboa, Portugal.</nlm:affiliation><country xml:lang="fr">Portugal</country><wicri:regionArea>Allergy and Clinical Immunology Department, Hospital CUF-Descobertas, Lisboa</wicri:regionArea><wicri:noRegion>Lisboa</wicri:noRegion></affiliation></author><author><name sortKey="Nogueira Silva, L" sort="Nogueira Silva, L" uniqKey="Nogueira Silva L" first="L" last="Nogueira-Silva">L. Nogueira-Silva</name><affiliation wicri:level="1"><nlm:affiliation>Center for Health Technology and Services Research - CINTESIS and Department of Internal Medicine, Centro Hospitalar Sao Joao, Porto, Portugal.</nlm:affiliation><country xml:lang="fr">Portugal</country><wicri:regionArea>Center for Health Technology and Services Research - CINTESIS and Department of Internal Medicine, Centro Hospitalar Sao Joao, Porto</wicri:regionArea><wicri:noRegion>Porto</wicri:noRegion></affiliation></author><author><name sortKey="O Hehir, R E" sort="O Hehir, R E" uniqKey="O Hehir R" first="R E" last="O'Hehir">R E O'Hehir</name><affiliation wicri:level="1"><nlm:affiliation>Department of Allergy, Immunology and Respiratory Medicine, Alfred Hospital and Central Clinical School, Monash University, Melbourne, Vic., Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Allergy, Immunology and Respiratory Medicine, Alfred Hospital and Central Clinical School, Monash University, Melbourne, Vic.</wicri:regionArea><wicri:noRegion>Vic.</wicri:noRegion></affiliation></author><author><name sortKey="Papadopoulos, N G" sort="Papadopoulos, N G" uniqKey="Papadopoulos N" first="N G" last="Papadopoulos">N G Papadopoulos</name><affiliation wicri:level="4"><nlm:affiliation>Center for Pediatrics and Child Health, Institute of Human Development, Royal Manchester Children's Hospital, University of Manchester, Manchester, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Center for Pediatrics and Child Health, Institute of Human Development, Royal Manchester Children's Hospital, University of Manchester, Manchester</wicri:regionArea><placeName><settlement type="city">Manchester</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Manchester</region><settlement type="city">Manchester</settlement></placeName><orgName type="university">Université de Manchester</orgName></affiliation></author><author><name sortKey="Passalacqua, G" sort="Passalacqua, G" uniqKey="Passalacqua G" first="G" last="Passalacqua">G. Passalacqua</name><affiliation wicri:level="1"><nlm:affiliation>Allergy and Respiratory Diseases, IRCCS San Martino-IST-University, Genoa, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Allergy and Respiratory Diseases, IRCCS San Martino-IST-University, Genoa</wicri:regionArea><wicri:noRegion>Genoa</wicri:noRegion></affiliation></author><author><name sortKey="Portejoie, F" sort="Portejoie, F" uniqKey="Portejoie F" first="F" last="Portejoie">F. Portejoie</name><affiliation wicri:level="3"><nlm:affiliation>MACVIA-France, Contre les MAladies Chroniques pour un VIeillissement Actif en France European Innovation Partnership on Active and Healthy Ageing Reference Site, Montpellier, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>MACVIA-France, Contre les MAladies Chroniques pour un VIeillissement Actif en France European Innovation Partnership on Active and Healthy Ageing Reference Site, Montpellier</wicri:regionArea><placeName><region type="region">Occitanie (région administrative)</region><region type="old region">Languedoc-Roussillon</region><settlement type="city">Montpellier</settlement></placeName></affiliation></author><author><name sortKey="Price, D" sort="Price, D" uniqKey="Price D" first="D" last="Price">D. Price</name><affiliation wicri:level="1"><nlm:affiliation>Observational and Pragmatic Research Institute, Singapore City, Singapore.</nlm:affiliation><country xml:lang="fr">Singapour</country><wicri:regionArea>Observational and Pragmatic Research Institute, Singapore City</wicri:regionArea><wicri:noRegion>Singapore City</wicri:noRegion></affiliation></author><author><name sortKey="Ryan, D" sort="Ryan, D" uniqKey="Ryan D" first="D" last="Ryan">D. Ryan</name><affiliation wicri:level="4"><nlm:affiliation>Allergy and Respiratory Research Group, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Allergy and Respiratory Research Group, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation></author><author><name sortKey="Samolinski, B" sort="Samolinski, B" uniqKey="Samolinski B" first="B" last="Samolinski">B. Samolinski</name><affiliation wicri:level="1"><nlm:affiliation>Department of Prevention of Environmental Hazards and Allergology, Medical University of Warsaw, Warsaw, Poland.</nlm:affiliation><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Prevention of Environmental Hazards and Allergology, Medical University of Warsaw, Warsaw</wicri:regionArea><wicri:noRegion>Warsaw</wicri:noRegion></affiliation></author><author><name sortKey="Sheikh, A" sort="Sheikh, A" uniqKey="Sheikh A" first="A" last="Sheikh">A. Sheikh</name><affiliation wicri:level="4"><nlm:affiliation>Centre of Medical Informatics, Usher Institute of Population Health Sciences and Informatics, The University of Edinburgh, Edinburgh, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre of Medical Informatics, Usher Institute of Population Health Sciences and Informatics, The University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation></author><author><name sortKey="Simons, F E R" sort="Simons, F E R" uniqKey="Simons F" first="F E R" last="Simons">F E R. Simons</name><affiliation wicri:level="4"><nlm:affiliation>Departments of Pediatrics & Child Health and Immunology, Faculty of Medicine, University of Manitoba, Winnipeg, MB, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Departments of Pediatrics & Child Health and Immunology, Faculty of Medicine, University of Manitoba, Winnipeg, MB</wicri:regionArea><orgName type="university">Université du Manitoba</orgName><placeName><settlement type="city">Winnipeg</settlement><region type="state">Manitoba</region></placeName></affiliation></author><author><name sortKey="Spranger, O" sort="Spranger, O" uniqKey="Spranger O" first="O" last="Spranger">O. Spranger</name><affiliation wicri:level="3"><nlm:affiliation>Global Allergy and Asthma Platform GAAPP, Vienna, Austria.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Global Allergy and Asthma Platform GAAPP, Vienna</wicri:regionArea><placeName><settlement type="city">Vienne (Autriche)</settlement><region nuts="2" type="province">Vienne (Autriche)</region></placeName></affiliation></author><author><name sortKey="Todo Bom, A" sort="Todo Bom, A" uniqKey="Todo Bom A" first="A" last="Todo Bom">A. Todo Bom</name><affiliation wicri:level="1"><nlm:affiliation>Imunoalergologia, Centro Hospitalar Universitário de Coimbra and Faculty of Medicine, University of Coimbra, Coimbra, Portugal.</nlm:affiliation><country xml:lang="fr">Portugal</country><wicri:regionArea>Imunoalergologia, Centro Hospitalar Universitário de Coimbra and Faculty of Medicine, University of Coimbra, Coimbra</wicri:regionArea><wicri:noRegion>Coimbra</wicri:noRegion></affiliation></author><author><name sortKey="Tomazic, P V" sort="Tomazic, P V" uniqKey="Tomazic P" first="P V" last="Tomazic">P V Tomazic</name><affiliation wicri:level="1"><nlm:affiliation>Department of ENT, Medical University of Graz, Graz, Austria.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Department of ENT, Medical University of Graz, Graz</wicri:regionArea><wicri:noRegion>Graz</wicri:noRegion></affiliation></author><author><name sortKey="Triggiani, M" sort="Triggiani, M" uniqKey="Triggiani M" first="M" last="Triggiani">M. Triggiani</name><affiliation wicri:level="1"><nlm:affiliation>Division of Allergy and Clinical Immunology, University of Salerno, Salerno, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Division of Allergy and Clinical Immunology, University of Salerno, Salerno</wicri:regionArea><wicri:noRegion>Salerno</wicri:noRegion></affiliation></author><author><name sortKey="Valero, A" sort="Valero, A" uniqKey="Valero A" first="A" last="Valero">A. Valero</name><affiliation wicri:level="3"><nlm:affiliation>Pneumology and Allergy Department, Ciberres and Clinical & Experimental Respiratory Imunoallergy, IDIBAPS, Universitat Barcelona, Barcelona, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Pneumology and Allergy Department, Ciberres and Clinical & Experimental Respiratory Imunoallergy, IDIBAPS, Universitat Barcelona, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Valovirta, E" sort="Valovirta, E" uniqKey="Valovirta E" first="E" last="Valovirta">E. Valovirta</name><affiliation wicri:level="4"><nlm:affiliation>Department of Lung Diseases and Clinical Immunology, University of Turku, Turku, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Lung Diseases and Clinical Immunology, University of Turku, Turku</wicri:regionArea><placeName><settlement type="city">Turku</settlement><region type="région" nuts="2">Finlande occidentale</region><settlement type="city">Turku</settlement></placeName><orgName type="university">Université de Turku</orgName></affiliation></author><author><name sortKey="Valiulis, A" sort="Valiulis, A" uniqKey="Valiulis A" first="A" last="Valiulis">A. Valiulis</name><affiliation wicri:level="1"><nlm:affiliation>Vilnius University Clinic of Children's Diseases and Public Health Institute, Vilnius, Lithuania.</nlm:affiliation><country xml:lang="fr">Lituanie</country><wicri:regionArea>Vilnius University Clinic of Children's Diseases and Public Health Institute, Vilnius</wicri:regionArea><wicri:noRegion>Vilnius</wicri:noRegion></affiliation></author><author><name sortKey="Van Eerd, M" sort="Van Eerd, M" uniqKey="Van Eerd M" first="M" last="Van Eerd">M. Van Eerd</name><affiliation wicri:level="1"><nlm:affiliation>Peercode DV, Gerdermalsen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Peercode DV, Gerdermalsen</wicri:regionArea><wicri:noRegion>Gerdermalsen</wicri:noRegion></affiliation></author><author><name sortKey="Wickman, M" sort="Wickman, M" uniqKey="Wickman M" first="M" last="Wickman">M. Wickman</name><affiliation wicri:level="3"><nlm:affiliation>Sachs' Children and Youth Hospital, Södersjukhuset, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Sachs' Children and Youth Hospital, Södersjukhuset, Institute of Environmental Medicine, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Young, I" sort="Young, I" uniqKey="Young I" first="I" last="Young">I. Young</name><affiliation wicri:level="1"><nlm:affiliation>Queen's University Belfast, Belfast, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Queen's University Belfast, Belfast</wicri:regionArea><wicri:noRegion>Belfast</wicri:noRegion></affiliation></author><author><name sortKey="Zuberbier, T" sort="Zuberbier, T" uniqKey="Zuberbier T" first="T" last="Zuberbier">T. Zuberbier</name><affiliation wicri:level="3"><nlm:affiliation>Global Allergy and Asthma European Network (GA2LEN), Comprehensive Allergy-Centre-Charité, Department of Dermatology and Allergy, Charité - Universitätsmedizin Berlin, Berlin, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Global Allergy and Asthma European Network (GA2LEN), Comprehensive Allergy-Centre-Charité, Department of Dermatology and Allergy, Charité - Universitätsmedizin Berlin, Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author></analytic><series><title level="j">Allergy</title><idno type="eISSN">1398-9995</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Allergic rhinitis often impairs social life and performance. The aim of this cross-sectional study was to use cell phone data to assess the impact on work productivity of uncontrolled rhinitis assessed by visual analogue scale (VAS). A mobile phone app (Allergy Diary, Google Play Store and Apple App Store) collects data from daily visual analogue scales (VAS) for overall allergic symptoms (VAS-global measured), nasal (VAS-nasal), ocular (VAS-ocular) and asthma symptoms (VAS-asthma) as well as work (VAS-work). A combined nasal-ocular score is calculated. The Allergy Diary is available in 21 countries. The app includes the Work Productivity and Activity Impairment Allergic Specific Questionnaire (WPAI:AS) in six EU countries. All consecutive users who completed the VAS-work from 1 June to 31 October 2016 were included in the study. A total of 1136 users filled in 5818 days of VAS-work. Symptoms of allergic rhinitis were controlled (VAS-global <20) in approximately 60% of the days. In users with uncontrolled rhinitis, approximately 90% had some work impairment and over 50% had severe work impairment (VAS-work >50). There was a significant correlation between VAS-global calculated and VAS-work (Rho=0.83, P<0.00001, Spearman's rank test). In 144 users, there was a significant correlation between VAS-work and WPAI:AS (Rho=0.53, P<0.0001). This pilot study provides not only proof-of-concept data on the work impairment collected with the app but also data on the app itself, especially the distribution of responses for the VAS. This supports the interpretation that persons with rhinitis report both the presence and the absence of symptoms.</div></front></TEI><affiliations><list><country><li>Allemagne</li><li>Australie</li><li>Autriche</li><li>Belgique</li><li>Brésil</li><li>Canada</li><li>Danemark</li><li>Espagne</li><li>Finlande</li><li>France</li><li>Irlande (pays)</li><li>Italie</li><li>Lituanie</li><li>Mexique</li><li>Pays-Bas</li><li>Pologne</li><li>Portugal</li><li>Royaume-Uni</li><li>Singapour</li><li>Suède</li></country><region><li>Angleterre</li><li>Bahia</li><li>Berlin</li><li>Catalogne</li><li>Finlande occidentale</li><li>Grand Londres</li><li>Grand Manchester</li><li>Hollande-Méridionale</li><li>Hollande-Septentrionale</li><li>Languedoc-Roussillon</li><li>Manitoba</li><li>Occitanie (région administrative)</li><li>Svealand</li><li>Vienne (Autriche)</li><li>Écosse</li><li>Île-de-France</li></region><settlement><li>Amsterdam</li><li>Barcelone</li><li>Berlin</li><li>Leyde</li><li>Londres</li><li>Manchester</li><li>Montpellier</li><li>Paris</li><li>Rotterdam</li><li>Stockholm</li><li>Turku</li><li>Vienne (Autriche)</li><li>Winnipeg</li><li>Édimbourg</li></settlement><orgName><li>Université d'Édimbourg</li><li>Université de Barcelone</li><li>Université de Manchester</li><li>Université de Turku</li><li>Université du Manitoba</li></orgName></list><tree><country name="France"><region name="Occitanie (région administrative)"><name sortKey="Bousquet, J" sort="Bousquet, J" uniqKey="Bousquet J" first="J" last="Bousquet">J. 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Larenas-Linnemann</name></noRegion></country><country name="Suède"><region name="Svealand"><name sortKey="Melen, E" sort="Melen, E" uniqKey="Melen E" first="E" last="Melén">E. Melén</name></region><name sortKey="Wickman, M" sort="Wickman, M" uniqKey="Wickman M" first="M" last="Wickman">M. Wickman</name></country><country name="Singapour"><noRegion><name sortKey="Price, D" sort="Price, D" uniqKey="Price D" first="D" last="Price">D. Price</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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